According to the latest estimates, the ad blocking user penetration rate in the United States stood at approximately 26 percent in 2020, indicating that roughly 73 million internet users had installed some form of ad blocking software, plugin, or browser on their web-enabled devices that year.
https://www.statista.com/topics/3201/ad-blocking/
Sounds like will affect 1/4 of youtube users. I highly doubt google would be doing this if it wasn’t getting in the way of making more money.