I never thought about it before but I use upstream and downstream without much though. For my personal devices and containers I use Fedora but when it comes to servers and VMs I use Debian for its stable nature.
I also run Linux mint in my homelab with pcie pass though so it functions like a normal desktop.
I use Debian on my servers, Arch on my laptop and desktop. Different tools for different jobs. I tried Debian on my laptop a few years ago but it wasn’t a good fit for me - my hardware was too new for the stable kernel, and the Wayland/wlroots stuff was too far behind. As a server though, especially since I’m mostly running Podman containers, stable and slow-updating is great! I use unattended-upgrades and haven’t had a problem yet.
I haven’t spent much time with Fedora but I’d probably like it as a desktop OS - fairly fast updates, and sticks pretty close to upstream without a ton of custom theming for example. I would miss the AUR, but Flatpak covers a lot of what I need, and Distrobox could handle anything else.