Interesting to see that I have pretty much the same (apparently wonky) setup with my ZigBee coordinator plugged into my Home Assistant mini-PC (via extension cable) in the basement of my house.
Though I have a better supported adapter (from Slaesh) it is definitely not in the middle of the house. It works fine so far with about 100 devices and it seems the backbone is strong enough so the basement location is not a big problem. Still I wonder if the mesh could be improved by getting a network-enabled adapter and placing it somewhere more central.
To add something here: HAProxy’s ACLs are more powerful than anything nginx, Apache or even Envoy can do. Of course HAProxy is not a web server but “just” a reverse proxy that speaks HTTP (and TCP) but what you can do with its ACLs is often extremely impressive in its simplicity and elegance. A single-line ACL in HAProxy would require loading additional modules in nginx and writing a screenful of configuration directives. Though the average self-hoster will probably never need any of the power HAProxy offers.
In the past 20 years I have professionally used all four of these as web servers and/or reverse proxies and I am pretty confident that HAProxy beats all others when it comes to request processing. Though Envoy might be getting there.